The Silence of the Lambs
Director: Jonathan Demme
Cast: Jodie Foster, Anthony Hopkins, Scott Glenn, Anthony Heald

A female FBI agent acquires help from one serial killer to catch another in this brilliantly acted psychological thriller. Anthony Hopkins is genuinely chilling in the male lead. The film won Academy Awards in all the five main categories. Based on a novel by Thomas Harris. Followed by Hannibal (sequel) and Red Dragon (prequel).